Barbiturates are CNS depressants. They are used therapeutically as sedatives, hypnotics, and anticonvulsants barbiturates are almost always taken orally as capsules or tablets. The effects resemble those of intoxication with alcohol. Chronic use of barbiturates leads to tolerance and physical dependence. Short-acting barbiturates taken at 400mg/day for 2-3 months can produce a clinically significant degree of physical dependence. Withdrawal symptoms experienced during periods of drug abstinence can be severe enough to cause death.

Only a small amount (less than 5%) of most barbiturates are excreted unaltered in the whole blood or serum or plasma.

The approximate detection time limits for barbiturates are:

Short acting (e.g. Secobarbital) 100 mg PO (oral) 4.5 days

long acting (e.g. Phenobarbital) 400 mg PO (oral) 7 days2

The Multi-Drug Rapid Test Cassette yields a positive result when the concentration of barbiturates in whole blood or serum or plasma exceeds 100ng/ml.

 

 

【DIRECTIONS FOR USE】

Allow the test, specimen, buffer and/or controls to reach room temperature (15-30°C) prior to testing.

For serum or plasma specimen:

1. Bring the pouch to room temperature (15-30℃) before opening it. Remove the cassette from the sealed pouch and use it within one hour.

2. Place the cassette on a clean and level surface. Hold the dropper vertically and transfer 1 full drop of serum or plasma (approximately 40 μl), then add 2 drops of buffer (approximately 80 μl) to the specimen well of the cassette, and then start the timer. Avoid trapping air bubbles in the specimen well. See illustration below.

3. Wait for the colored line(s) to appear. Read the result at 5 minutes. Do not interpret the result after 10 minutes.

 

For whole blood specimen:

1. Bring the pouch to room temperature before opening it. Remove the test cassette from the sealed pouch and use it as soon as possible.

2. Place the cassette on a clean and level surface.

For Venipuncture Whole Blood specimen:

 Hold the dropper vertically and transfer 1 drop of whole blood (approximately 40 μl) to the specimen well, then add 2 drops of buffer (approximately 80 μl), and start the timer. See illustration below.

For Fingerstick Whole Blood specimen:

 To use a capillary tube: Fill the capillary tube and transfer approximately 40 μl of fingerstick whole blood specimen to the specimen area of test cassette, then add 2 drops of buffer(approximately 80 μl) and start the timer. See illustration below.

3. Wait for the colored line(s) to appear. Read results at 5 minutes. Do not interpret the result after 10 minutes.

 

 

 

 

 

 

Cat. No.	Product Description	Specimen	Format	Kit Size	Cut-Off	Status
DBA-402	BAR Rapid Test Cassette	WB/S/P	Cassette	40 T	100 ng/mL	CE