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203, Jalan Bukit Bintang,
55100 Kuala Lumpur,
Malaysia.
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Setia Scientific Solution
Suite 33-01, 33rd Floor, Menara Keck Seng,
203, Jalan Bukit Bintang,
55100 Kuala Lumpur,
Malaysia.
Suite 33-01, 33rd Floor, Menara Keck Seng,
203, Jalan Bukit Bintang,
55100 Kuala Lumpur,
Malaysia.
Cotinine (COT) Rapid Test - Urine
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¡¾SUMMARY¡¿
Cotinine is the first-stage metabolite of nicotine, a toxic alkaloid that produces stimulation of the autonomic ganglia and central nervous system when in humans. Nicotine is a drug to which virtually every member of a tobacco-smoking society is exposed whether through direct contact or second-hand inhalation. In addition to tobacco, nicotine is also commercially available as the active ingredient in smoking replacement therapies such as nicotine gum, transdermal patches and nasal sprays.
In a 24-hour urine, approximately 5% of a nicotine dose is excreted as unchanged drug with 10% as cotinine and 35% as hydroxycotinine; the concentrations of other metabolites are believed to account for less than 5%.1 While cotinine is thought to be an inactive metabolite, it’s elimination profile is more stable than that of nicotine which is largely urine pH dependent. As a result, cotinine is considered a good biological marker for determining nicotine use. The plasma half-life of nicotine is approximately 60 minutes following inhalation or parenteral administration.
¡¾DIRECTIONS FOR CASSETTE USE¡¿
Allow the test, urine specimen, and/or controls to reach room temperature (15-30°C) prior to testing.
1. Bring the pouch to room temperature before opening it. Remove the test cassette from the sealed pouch and use it within one hour.
2. Place the test cassette on a clean and level surface. Hold the dropper vertically and transfer 3 full drops of urine (approx. 120μL) to the specimen well (S) of the test cassette, and then start the timer. Avoid trapping air bubbles in the specimen well (S). See the illustration below.
3. Wait for the colored line(s) to appear. Read results at 5 minutes. Do not interpret the result after 10minutes.
_Rapid_Test___Urine.jpg)
¡¾DIRECTIONS FOR PANEL USE¡¿
Allow the test, urine specimen, and/or controls to reach room temperature (15-30ºC) prior to testing.
1. Bring the pouch to room temperature before opening it. Remove the test panel from the sealed pouch and use it within one hour.
2. Remove the cap.
3. With the arrow pointing toward the urine specimen, immerse the test panel vertically in the urine specimen for at least 10 to 15 seconds. Immerse the strip to at least the level of the wavy lines, but not above the arrow on the test panel.
4. Replace the cap and place the test panel on a non-absorbent flat surface.
5. Start the timer and wait for the colored line(s) to appear.
6. The result should be read at 5 minutes. Do not interpret the result after 10 minutes.
_Rapid_Test___Urine1.jpg)
¡¾DIRECTIONS FOR DIPSTICK USE¡¿
Allow the test, urine specimen, and/or controls to reach room temperature (15-30ºC) prior to
testing.
1. Bring the pouch to room temperature before opening it. Remove the test dipstick from the sealed pouch and use it within one hour.
2. With arrows pointing toward the urine specimen, immerse the test dipstick vertically in the urine specimen for at least 10-15 seconds. Do not pass the maximum line (MAX) on the Test Dipstick when immersing the strip. See the illustration below.
3. Place the test dipstick on a non-absorbent flat surface, start the timer and wait for the colored line(s) to appear. Read results at 5 minutes. Do not interpret the result after 10 minutes.
_Rapid_Test___Urine2.jpg)
|
Cat. No. |
Product Description |
Specimen |
Format |
Kit Size |
Cut-Off |
Status |
|
DCT-102 |
Cotinine (COT) Rapid Test Cassette |
Urine |
Cassette |
40 T |
10 ng/mL, 50 ng/mL, |
CE |
|
DCT-114 |
Cotinine (COT) Rapid Test Panel |
Urine |
Panel |
40 T |
CE |
|
|
DCT-101 |
Cotinine (COT) Rapid Test Dipstick |
Urine |
Dipstick |
50 T |
CE |