TCA (Tricyclic Antidepressants) are commonly used for the treatment of depressive disorders. TCA overdoses can result in profound CNS depression, cardiotoxicity and anticholinergic effects. TCA overdose is the most common cause of death from prescription drugs. TCA are taken orally or sometimes by injection. TCA are metabolized in the liver. Both TCA and their metabolites are excreted in whole blood or serum or plasma mostly in the form of metabolites for up to ten days.

 

【DIRECTIONS FOR USE】

Allow the test, specimen, buffer and/or controls to reach room temperature (15-30°C) prior to testing.

For serum or plasma specimen:

1. Bring the pouch to room temperature (15-30℃) before opening it. Remove the cassette from the sealed pouch and use it within one hour.

2. Place the cassette on a clean and level surface. Hold the dropper vertically and transfer 1 full drop of serum or plasma (approximately 40µL), then add 2 drops of buffer (approximately 80µL) to the specimen well of the cassette, and then start the timer. Avoid trapping air bubbles in the specimen well. See illustration below.

3. Wait for the colored line(s) to appear. Read the result at 5 minutes. Do not interpret the result after 10 minutes.

 

 

 

For whole blood specimen:

1. Bring the pouch to room temperature before opening it. Remove the test cassette from the sealed

pouch and use it as soon as possible.

2. Place the cassette on a clean and level surface.

For Venipuncture Whole Blood specimen:

 Hold the dropper vertically and transfer 1 drop of whole blood (approximately 40µL) to the specimen well, then add 2 drops of buffer (approximately 80µL), and start the timer. See illustration below.

For Fingerstick Whole Blood specimen:

 To use a capillary tube: Fill the capillary tube and transfer approximately 40µL of fingerstick whole blood specimen to the specimen area of test cassette, then add 2 drops of buffer(approximately 80µL) and start the timer. See illustration below.

3.Wait for the colored line(s) to appear. Read results at 5 minutes. Do not interpret the result after 10 minutes.