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MDPV Rapid Test Cassette - WB/S/P

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MDPV Rapid Test Cassette - WB/S/P JusChek Drug of Abuse Rapid Test


¡¾SUMMARY¡¿
3, 4-methylenedioxypyrovalerone (MDPV) is a psychoactive recreational drug with stimulant properties which acts as a norepinephrine-dopamine reuptake inhibitor (NDRI). It was first developed in the 1960s by a team at Boehringer Ingelheim. MDPV remained an obscure stimulant until around 2004 when it was reportedly sold as a designer drug. Products labeled as bath salts containing MDPV were previously sold as recreational drugs in gas stations and convenience stores in the United States, similar to the marketing for Spice and K2 as incense. MDPV is the 3,4-methylenedioxy ring-substituted analog of the compound pyrovalerone, developed in the 1960s, which has been used for the treatment of chronic fatigue and as an anorectic, but caused problems of abuse and dependence. However, despite its structural similarity, the effects of MDPV bear little resemblance to other methylenedioxy phenylalkylamine derivatives such as 3,4-methylenedioxy-N-methylamphetamine (MDMA), instead producing primarily stimulant effects with only mild entactogenic qualities. MDPV undergoes CYP450 2D6, 2C19, 1A2, and COMT phase 1 metabolism (liver) into methylcatechol and pyrrolidine, which in turn are glucuronated (uridine 5'-diphospho-glucuronosyl-transferase) allowing it to be excreted by the kidneys, with only a small fraction of the metabolites being excreted into the stools. No free pyrrolidine will be detected in the urine.
 
 
 
¡¾DIRECTIONS FOR USE¡¿
Allow the test, specimen, buffer and/or controls to reach room temperature (15-30°C) prior to testing.
For serum or plasma specimen:
1. Bring the pouch to room temperature (15-30¡æ) before opening it. Remove the cassette from the sealed pouch and use it within one hour.
2. Place the cassette on a clean and level surface. Hold the dropper vertically and transfer 1 full drop of serum or plasma (approximately 40μl), then add 2 drops of buffer (approximately 80 μl) to the specimen well of the cassette, and then start the timer. Avoid trapping air bubbles in the specimen well. See illustration below.
3. Wait for the colored line(s) to appear. Read the result at 5 minutes. Do not interpret the result after 10 minutes.
 

 
For whole blood specimen:
4. Bring the pouch to room temperature before opening it. Remove the test cassette from the sealed pouch and use it as soon as possible.
5. Place the cassette on a clean and level surface.
For Venipuncture Whole Bloodspecimen:
 Hold the dropper vertically and transfer 1 drop of whole blood(approximately 40 μl) to the specimen well, then add 2 drops of buffer (approximately 80 μl), and start the timer. See illustration below.
For Fingerstick Whole Blood specimen: 
 To use a capillary tube: Fill the capillary tube and transfer approximately 40 μl of fingerstick whole blood specimen to the specimen area of test cassette, then add2 drops of buffer(approximately 80 μl) and start the timer. See illustration below.
6. Wait for the colored line(s) to appear. Read results at 5 minutes. Do not interpret the result after 10 minutes.
 
 

 

 

 

 

Cat. No.

Product Description

Specimen

Format

Kit Size

Cut-Off

Status

DMDP-402

MDPV Rapid Test Cassette

WB/S/P

Cassette

40 T

300 ng/mL

CE


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