Methylenedioxymethamphetamine (ecstasy) is a designer drug first synthesized in 1914 by a German drug company for the treatment of obesity. Those who take the drug frequently report adverse effects, such as increased muscle tension and sweating. MDMA is not clearly a stimulant, although it has, in common with amphetamine drugs, a capacity to increase blood pressure and heart rate. MDMA does produce some perceptual changes in the form of increased sensitivity to light, difficulty in focusing, and blurred vision in some users. Its mechanism of action is thought to be via release of the neurotransmitter serotonin. MDMA may also release dopamine, although the general opinion is that this is a secondary effect of the drug (Nichols and Oberlender, 1990). The most pervasive effect of MDMA, occurring in virtually all people who took a reasonable dose of the drug, was to produce a clenching of the jaws.

The MDMA assay contained within the Multi-Drug Rapid Test Cassette/Midstream yields a positive result when the MDMA concentration in saliva exceeds 50ng/ml.

 

【DIRECTIONS FOR CASSETTE USE】
Allow the test cassette, specimen, and/or controls to reach room temperature (15-30ºC) prior to testing. Instruct the donor to not place anything in the mouth including food, drink, gum or tobacco products for at least 10 minutes prior to collection.
1. Bring the pouch to room temperature before opening it. Remove the test cassette from the sealed pouch and use it within one hour.
2. Remove the collector from the sealed pouch and insert the sponge end of the collector into the mouth. Actively swab the inside of the mouth and tongue to collect oral fluid for a total of 3 minutes until the sponge becomes fully saturated. Gentle pressing the sponge between the tongue and teeth will assist saturation. No hard spots should be felt on the sponge when saturated.
3. Remove the collector from the mouth. Place saturated oral fluid collector into chamber and press sponge fully against the strainer to collect oral fluid. Discard the collector. Snap the cap shut on the collection tube.
4. Place the test cassette on a clean and level surface. Unscrew cap cover from the collection tube. Invert the collection tube and transfer 3 drops of oral fluid (approximately 120 µL) into specimen well of the test cassette and start the timer. Avoid trapping air bubbles in the specimen well. Place screw cap on the collection tube. See illustration below.
5. Wait for the colored line(s) to appear. Read results at 10 minutes. Do not read results after 1 hour.

 

【DIRECTIONS FOR DEVICE USE】

Allow the test device, specimen, and/or controls to reach room temperature (15-30ºC) prior to testing. Instruct the donor to not place anything in the mouth including food, drink, gum or tobacco products for at least 10 minutes prior to collection.

1. Remove the test device from the sealed pouch and use it within one hour.

2. Take off the device cap and insert the absorbent wick to the mouth, put it under the tongue to collect oral fluid until the control line appears.

3. Put the device cap back outside of the absorbent wick and lace the test midstream on a clean and level surface. See illustration below.

4. Read results at 10 minutes. Do not read results after 1 hour.