Cocaine is a potent central nervous system (CNS) stimulant and a local anesthetic derived from the coca plant (erythroxylum coca). The drug is often self-administered by nasal inhalation, intravenous injection and free-base smoking. Depending on the route of administration, cocaine and metabolites benzoylecgonine and ecgonine methyl ester can be detected in oral fluid as early as 5-10 minutes following use. Cocaine and benzoylecgonine can be detected in oral fluids for up to 24 hours after use.

The cocaine assay contained within the Multi-Drug Rapid Test Cassette/ Midstream for cocaine and opiates yields a positive result when the cocaine metabolite in oral fluid exceeds 20ng/ml.

 

 

【DIRECTIONS FOR CASSETTE USE】
Allow the test cassette, specimen, and/or controls to reach room temperature (15-30ºC) prior to testing. Instruct the donor to not place anything in the mouth including food, drink, gum or tobacco products for at least 10 minutes prior to collection.
1. Bring the pouch to room temperature before opening it. Remove the test cassette from the sealed pouch and use it within one hour.
2. Remove the collector from the sealed pouch and insert the sponge end of the collector into the mouth. Actively swab the inside of the mouth and tongue to collect oral fluid for a total of 3 minutes until the sponge becomes fully saturated. Gentle pressing the sponge between the tongue and teeth will assist saturation. No hard spots should be felt on the sponge when saturated.
3. Remove the collector from the mouth. Place saturated oral fluid collector into chamber and press sponge fully against the strainer to collect oral fluid. Discard the collector. Snap the cap shut on the collection tube.
4. Place the test cassette on a clean and level surface. Unscrew cap cover from the collection tube. Invert the collection tube and transfer 3 drops of oral fluid (approximately 120 µL) into specimen well of the test cassette and start the timer. Avoid trapping air bubbles in the specimen well. Place screw cap on the collection tube. See illustration below.
5. Wait for the colored line(s) to appear. Read results at 10 minutes. Do not read results after 1 hour.