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IgE Rapid Test Cassette

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IgE Rapid Test Cassette JusChek Others Rapid Test


¡¾SUMMARY¡¿
Immunoglobulin E (IgE) is a type of antibody (or immunoglobulin (Ig) ''isotype'') that has only been found in mammals. IgE is synthesised by plasma cells. Monomers of IgE consist of two heavy chains (ε chain) and two light chains, with the ε chain containing 4 Ig-like constant domains (Cε1-Cε4). IgE's main function is immunity to parasites such as helminths like Schistosoma mansoni, Trichinella spiralis, and Fasciola hepatica.IgE is utilized during immune defense against certain protozoan parasites such as Plasmodium falciparum.

IgE also has an essential role in type I hypersensitivity, which manifests in various allergic diseases, such as allergic asthma, most types of sinusitis, allergic rhinitis, food allergies, and specific types of chronic urticaria and atopic dermatitis. IgE also plays a pivotal role in responses to allergens, such as: anaphylactic drugs, bee stings, and antigen preparations used in desensitization immunotherapy.
Although IgE is typically the least abundant isotype—blood serum IgE levels in a normal (''non-atopic'') individual are only 0.05% of the Ig concentration,8compared to 75% for theIgGs at 10 mg/ml, which are the isotypes responsible for most of the classical adaptive immune response—it is capable of triggering the most powerful inflammatory reactions.

¡¾DIRECTIONS FOR USE¡¿
Allow the test, specimen, buffer and/or controls to reach room temperature (15-30°C) prior to testing.
1. Bring the pouch to room temperature before opening it. Remove the test cassette from the sealed pouch and use it within 1 hour.
2. Place the cassette on a clean and level surface.
For Serum or Plasma specimen:
Hold the dropper vertically and transfer 2 drops of serum or plasma (approximately 50μL) to the specimen well, and start the timer. See illustration below.
For Venipuncture Whole Blood specimen:
Hold the dropper vertically and transfer 3 drops of whole blood (approximately 75μL) to the specimen well, then add 1 drop of buffer (approximately 40μL), and start the timer. See illustration below.
For Fingerstick Whole Blood specimen:
Fill the capillary tube and transfer approximately 75μL of fingerstick whole blood specimen to the specimen well of test cassette, then add 1 drop of buffer (approximately 40μL) and start the timer. See illustration below.
3. Wait for the colored line(s) to appear. Read results at 5 minutes. Do not interpret the result after 10 minutes.Note: It is suggested not to use the buffer, beyond 6 months after opening the vial.

 

Cat. No.

Product Description

Specimen

Format

Kit Size

Cut-Off

Status

OIGE-402

IgE Rapid Test Cassette

WB/S/P

Cassette

10 T

200IU/mL

CE


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